How does orlistat work?
Many people wonder how orlistat helps with weight loss, and with good reason! It’s always important to know how your medicines work in your body to understand how they help you. Orlistat is a lipase inhibitor, and it works in your digestive system. Lipases are enzymes that are produced by the pancreas when fat is detected. These enzymes help your body to digest the fat by breaking them down into smaller parts to be stored for energy. Orlistat works by interfering with this process and attaches to the lipases. This stops the enzymes from breaking down around 1/3 of the fat that you ingest, ultimately reducing your calorie and fat intake by getting rid of it through your stools. For example, without orlistat, you may absorb 6 grams of fat from a meal. With orlistat, weight loss should be a consequence of the drug only letting your body absorb 4 grams of fat from the same meal. The extra 2 grams should then be expelled by the body through your poo. Orlistat should always be used in conjunction with a low fat and low calorie diet, as well as increased exercise. This is so that the drug can work to its full potential. It isn’t a substitute for a healthy lifestyle, but it can help many obese people that struggle with weight loss through diet and exercise alone.
Orlistat side effects
Due to the way orlistat works in your body, it can cause some unpleasant side effects. Most people that take orlistat capsules find that the side effects are bearable, or that they subside a few weeks after you start treatment, but it’s important to be aware of them so that you aren’t shocked if you do experience them. Many of the side effects are gastrointestinal, but provided that you stick to the recommended low-fat diet, they shouldn’t be too severe. However, if you decide that the side effects do outweigh the benefits of the medication, it might be a good idea to stop treatment and look at other weight loss aids such as Saxenda. Some of orlistat’s side effects include: